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Neurological Studies
Memory Loss
Current, past, and upcoming studies include:
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Many phase 2 & 3 pharmaceutical trials for Early Memory Loss and Alzheimer's Disease, including a multicentre, multinational study for the safety and efficacy of a study medication for slowing disease progression in people with early memory loss.
Pain Studies
Current, past and upcoming studies include:
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Post-operative pain management following laparoscopic cholecystostomy.
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Post-operative pain management following arthroscopic shoulder surgery and arthroscopic knee surgery.
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Evaluation of effectiveness of a new medication for chronic knee or back pain.
Our Studies
Surgical & Orthopaedic Studies
Osteo-integration
Current, past and upcoming studies include:
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Evaluation of Prosthesis effectiveness in Oxford knee replacement.
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Total hip replacement.
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Acetabular implant surgery.
Pain Studies
Current, past and upcoming studies include:
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Lower back pain and osteoarthritis of the knee.
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Chronic moderate to severe pain in osteoarthritis.
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Evaluation of medication for pain in end stage joint disease.
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Post-operative pain following arthroscopic knee surgery.
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Post-operative pain management following arthroscopic shoulder surgery.
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Post-operative pain management following laparoscopic cholecystestomy.
New Device
Current, past and upcoming studies include:
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Evaluation of new stoma devices.
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Orthopaedic fixation & replacement devices.
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Pain relief delivery systems.
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Investigation of knee replacement implants for patients with osteoarthritis.
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Investigation of hip replacement implants.
Fracture Healing
Current, past and upcoming studies include:
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Evaluation of the effectiveness and safety of a medication to promote healing post tibial fracture fixation.
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Evaluation of the effectiveness and safety of a medication to promote healing in intertrochanteric fracture post fixation.
Paget's Disease
Current, past and upcoming studies include:
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An international trial for the prevention of Paget's disease in patients with a familial mutation.
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We have completed previous multi-centre pharmaceutical trials in patients with Paget's disease.
Metabolic Bone Studies
Bone Mineral Density
Current, past and upcoming studies include:
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Our GE Lunar iDXA Bone Mineral Densitometer scanner and trained densitometrists have enabled us to perform many pharmaceutical studies in the prevention and treatment of osteoporosis for both women & men, for patients undergoing chemotherapy and for those who have had spinal cord injury.
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Numerous studies assessing bone mineral density around joint implants.
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iDXA scanner software development for assessment of knee implants.
Osteoporosis
Current, past and upcoming studies include:
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Studies to assess the effectiveness and safety of new medications for the treatment of postmenopausal women with osteoporosis.
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Studies to evaluate the effectiveness and safety of new medications for postmenopausal women with vertebral fracture.
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Studies to investigate the effectiveness of new medications in the prevention of vertebral fractures in postmenopausal women with low bone mass.
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Studies to assess the safety and effectiveness of new medications to reduce the risk of fracture in osteoporotic postmenopausal women.
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Observational studies of the rate of fractures in patients on therapy for osteoporosis.
Bone Markers
Current, past and upcoming studies include:
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Many studies assessing change in bone markers in various metabolic bone diseases.
Arthritis Studies
Rheumatoid Arthritis
Current, past and upcoming studies include:
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A Rheumatoid Arthritis study into Methotrexate.
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Studies to assess the effectiveness, safety and tolerability of new medications on patients with active Rheumatoid Arthritis who are inadequate responders to MTX therapy.
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Studies to assess the effectiveness and safety of new medications to prevent structural damage in patients with active Rheumatoid Arthritis.
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Studies to assess the safety and effectiveness of new medications in patients with active Rheumatoid Arthritis.
Osteoarthritis
Current, past and upcoming studies include:
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A study into osteoarthritis of the knee for those with a primary diagnoses of primary tibiofemoral knee Osteoarthritis on X-Ray
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A study in patients with osteoarthtritis to determine the incidence of treatment induced gastroduodenal ulcers.
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Completed trials for osteoarthritic pain.
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Post-operative bone quality around joint replacements.
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Evaluation of new devices & instrumentation in joint replacement surgery.
Psoriatic Arthritis Studies
Current, past and upcoming studies include:
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A study to evaluate the effectiveness and safety of a new medications for patients with Active Psoriatic Arthritis.
Polymyalgia Rheumatica (PMR)
Current, past and upcoming studies include:
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A multi-centre, world-wide study to demonstrate the effectiveness and safety of a new medication for patients aged 50 and over.
Opthalmology / Eye Studies
Southern Eye Specialists
Current, past and upcoming studies include:
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A collaboration with Southern Eye Specialists in several eye studies in subjects with Macular Degeneration.
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A Retinal Vein Occlusion study to assess the efficacy of a suprachoroidally injected study treatment.
Giant Cell Arteritis
Current, past and upcoming studies include:
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Multi-centre global trial to test the effectiveness and safety of study medication for patients with recently diagnosed Giant Cell Arteritis, or who are suffering recent relapse with Giant Cell Arteritis.
Other Studies
Sarcopenia
Current, past and upcoming studies include:
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Sarcopenia (muscle wasting) studies.
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In conjunction with another research unit, CCST, we have utilised a bone density (iDXA) machine in Phase 1 trials to assess the safety & effectiveness of study medication in reducing age related muscle wasting, using Body Composition Application.
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A study to evaluate the safety and effectiveness of a new medication in women with low muscle mass using Body Composition Application.
Nutrition
Current, past and upcoming studies include:
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A double-blind, placebo-controlled, pilot study on the effect of dietary supplementation on quality of life, neuromuscular balance, vision, and the markers of oxidative damage on healthy elderly participants.
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A study to assess the effects of dietary supplementation in adolescent girls.
Vaccines
Current, past and upcoming studies include:
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Several multicenter international vaccines studies for infections such as influenza and pneumonia.
Respiratory/Cough
Current, past and upcoming studies include:
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A study of the treatment of acute exacerbation of Chronic Bronchitis in adult patients in the community with Chronic Obstructive Pulmonary Disease (COPD).
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Comparison of the effectiveness and adverse effect profile of a study drug in hospitalised patients with pneumonia and exacerbations of chronic Bronchitis/COPD.
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Studies to investigate the incidence of cough in patients receiving ACE Inhibitors.
Stoma Studies
Current, past and upcoming studies include:
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Assessing the effectiveness, tolerability and assessment of wear time of new ostomy devices.
Gastroduodenal Ulcers
Current, past and upcoming studies include:
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Endoscopic assessment of the effectiveness of various medications in patients with duodenal and gastric drug-related ulcers.
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A study of the incidence of gastroduodenal ulcers in patients on osteoarthritis treatment.